ICMART

GLOSSARY

The International Glossary on Infertility and Fertility Care

The following glossary was developed in 2017 by a global panel of more than 100 multidisciplinary experts, professional organisations, and patient representatives to provide consensus agreement on 283 items and definitions. Published in Fertility and Sterility (FNS) and Human Reproduction (HR).
A printable version of the 2017 Glossary and more information on the methodology, and a list of previous compiled glossaries can be found here.

Thawing

The process of raising the temperature of slow-frozen cell(s) from the storage temperature to room/physiological temperature.

Time to pregnancy (TTP)

The time taken to establish a pregnancy, measured in months or in numbers of menstrual cycles.

Time-lapse imaging

The photographic recording of microscope image sequences at regular intervals in ART, referring to gametes, zygotes, cleavage-stage embryos or blastocysts.

Total delivery rate with at least one live birth

The total number of deliveries with at least one live birth resulting from one initiated or aspirated ART cycle, including all cycles in which fresh and/or frozen embryos are transferred, including more than one delivery from one initiated or aspirated cycle if that occurs, until all embryos are used. Notes: The delivery of a singleton, twin or other multiple pregnancy is registered as one delivery. In the absence of complete data, the total delivery rate is often estimated.

Total fertility rate (TFR)

The average number of live births per woman. It may be determined in retrospect, observed data (Cohort Total Fertility Rate, CTFR) or as an estimated average number (Period Total Fertility Rate, PTFR).

Total sperm count

A woman who donates her oocytes and is the gestational carrier for a pregnancy resulting from fertilization of her oocytes either through an ART procedure or insemination. This replaces the term ‘traditional surrogate.’

Traditional gestational carrier

A woman who donates her oocytes and is the gestational carrier for a pregnancy resulting from fertilization of her oocytes either through an ART procedure or insemination. This replaces the term ‘traditional surrogate.’

Trisomy

An abnormal number of chromosome copies in a cell characterized by the presence of three homologous chromosomes rather than the normal two. The majority of human embryos with trisomies are incompatible with life.

Trophectoderm

Cells forming the outer layer of a blastocyst that have the potential to develop into the placenta and amniotic membranes.

Tubal pathology

Tubal abnormality resulting in dysfunction of the Fallopian tube, including partial or total obstruction of one or both tubes (proximally, distally or combined), hydrosalpinx and/or peri-tubal and/or periovarian adhesions affecting the normal ovum pick-up function. It usually occurs after pelvic inflammatory disease or pelvic surgery.

Unexplained infertility

Infertility in couples with apparently normal ovarian function, Fallopian tubes, uterus, cervix and pelvis and with adequate coital frequency; and apparently normal testicular function, genito-urinary anatomy and a normal ejaculate. The potential for this diagnosis is dependent upon the methodologies used and/or those methodologies available.

Unisomy

The condition in a cell resulting from loss of a single chromosome yielding a single copy of that particular chromosome rather than the normal two. The majority of unisomies in human embryosare incompatible with life.

Vaginal insemination

A procedure whereby semen, collected from a non-lubricated condom or similar method, is deposited into the vaginal cavity of a female. An intervention that can be self-administered by a woman attempting pregnancy.

Varicocele

A venous enlargement in the testicular pampiniform plexus.

Varicocelectomy

Procedure to occlude or remove part of the internal spermatic vein in situations in which it has expanded into a varicocele.

Vasectomy

Procedure to occlude the vas deferens. It is usually carried out bilaterally in order to secure sterilization.

Very low birth weight

Birth weight less than 1500 g.

Viscosity

The description of the relative fluidity of the semen.

Vitrification

An ultra-rapid cryopreservation procedure that prevents ice formation within a cell whose aqueous phase is converted to a glass-like solid.

Voluntary childlessness

A condition describing a person who does not have or has not had a child wish and does not have any biologically, legally or societally-recognized children.
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