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GLOSSARY

The International Glossary on Infertility and Fertility Care

The following glossary was developed in 2017 by a global panel of more than 100 multidisciplinary experts, professional organisations, and patient representatives to provide consensus agreement on 283 items and definitions. Published in Fertility and Sterility (FNS) and Human Reproduction (HR).
A printable version of the 2017 Glossary and more information on the methodology, and a list of previous compiled glossaries can be found here.

Cumulative delivery rate per aspiration/initiated cycle with at least one live birth

The number of deliveries with at least one live birth resulting from one initiated or aspirated ART cycle, including all cycles in which fresh and/or frozen embryos are transferred, until one delivery with a live birth occurs or until all embryos are used, whichever occurs first. The delivery of a singleton, twin, or other multiples is registered as one delivery. In the absence of complete data, the cumulative delivery rate is often estimated.

Cumulus oophorus

The multi-layered mass of granulosa cells surrounding the oocyte.

Cytoplasmic maturation

The process during which the oocyte acquires the capacity to support nuclear maturation, fertilization, pronuclei formation, syngamy and subsequent early cleavage divisions until activation of the embryonic genome.

Cytoplasmic transfer

A procedure that can be performed at different stages of an oocyte’s development to add to or replace various amounts of cytoplasm from a donor egg.

Decreased spermatogenesis

A histological finding in which spermatogenesis is present with few cells in the seminiferous tubules, resulting in a decreased number or absence of sperm in the ejaculate.

Delayed ejaculation

A condition in which it takes a man an extended period of time to reach orgasm and ejaculation.

Delayed embryo transfer

A procedure in which embryo transfer is not performed within the time frame of the oocyte aspiration cycle but at a later time

Delivery

The complete expulsion or extraction from a woman of one or more fetuses, after at least 22 completed weeks of gestational age, irrespective of whether they are live births or stillbirths. A delivery of either a single or multiple newborn is considered as one delivery. If more than one newborn is delivered, it is often recognized as a delivery with multiple births.

Delivery rate

The number of deliveries expressed per 100 initiated cycles, aspiration cycles, or embryo transfer cycles. When delivery rates are recorded, the denominator (initiated, aspirated or embryo transfer cycles) must be specified. It includes deliveries that resulted in the birth of one or more live births and/or stillbirths. The delivery of a singleton, twin or other multiple pregnancy is registered as one delivery. If more than one newborn is delivered, it is often recognized as a delivery with multiple births.

Delivery rate after fertility treatment per patient

The number of deliveries with at least one live birth or stillbirth, expressed per 100 patients, after a specified time and following all treatments.

Delivery with multiple births after fertility treatments

A single delivery with more than one newborn, following all fertility treatments.

Diandric oocytes

An oocyte with an extra set of haploid chromosomes of paternal origin.

Digynic oocytes

An oocyte with an extra set of haploid chromosomes of maternal origin.

Diminished ovarian reserve

A term generally used to indicate a reduced number and/or reduced quality of oocytes, such that the ability to reproduce is decreased. (See ovarian reserve.)

Diploidy/euploidy

The condition in which a cell has two haploid sets of chromosomes. Each chromosome in one set is paired with its counterpart in the other set. A diploid embryo has 22 pairs of autosomes and two sex chromosomes, the normal condition.

Disomy

The normal number of chromosomes characterized by 22 pairs of autosomal chromosomes and one pair of sex chromosomes (XX or XY). The chromosome number in human cells is normally 46.

Donor insemination

The process of placing laboratory processed sperm or semen from a man into the reproductive tract of a woman who is not his intimate sexual partner, for the purpose of initiating a pregnancy.

Double embryo transfer (DET)

The transfer of two embryos in an ART procedure. This may be elective (eDET) when more than two embryos of sufficient quality for transfer are available.
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